About MolMeDB
MolMeDB (Molecules on Membranes Database) is an open, comprehensive and interactive database about interactions of (small) molecules. The database primarily contains information on interactions of molecules with biomembranes (passive interactions) and is gradually supplemented by interactions of molecules with molecular transporters (active interactions). Data is obtained from the publicly-accessible literature; however, their inconsistent format and small amount do not provide sufficient insight to understand the related issues. For that reason, most of the data is obtained by in-house calculations simulating the penetration of a molecule through the membrane and computing the details of their interactions.
How do compounds interact with membranes?
- They are attracted to membranes,
- they partition to membranes,
- they reside in specific positions in membranes,
- they permeate through membranes
- they change the membranes,
- and many more.
These interactions are subjected to many kinds of research, but data spread across many publications can significantly complicate needed analyses. MolMeDB was created as a centralized repository of molecule-membrane interactions to facilitate the retrieval of these data in readable formats.
This document describes what and how information can be retrieved from the MolMeDB database. For the comprehensive description of data stored in MolMeDB, please see Database content section. If you are interested in easily-obtaining data, please see REST API section.
How to cite
Juracka J., Šrejber M., Melíková M., Bazgier V., Berka K.: MolMeDB: Molecules on Membranes Database.
Database, Volume 2019, 2019, baz078, https://doi.org/10.1093/database/baz078
It is also advisable to cite used datasets.
Fairsharing DOI: https://fairsharing.org/FAIRsharing.CWzk3C
License of use
CC-BY
Financial support
- GAČR 17-2112S (Principal investigator: doc. RNDr. Karel Berka, Ph.D.)
- Palacky University Olomouc (projects IGA_PrF_2018_032 and IGA_2019_031).
- ELIXIR-CZ (projects LM2015047 and LM2018131).